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【Objective】 To establish the quantitative classification model of blood inventory warning for public health emergencies, so as to provide reference for practical application. 【Methods】 The classification model of blood inventory early warning for public health emergencies was constructed through literature review, fuzzy comprehensive evaluation method and analytic hierarchy process (AHP). The constructed model was used to conduct fuzzy comprehensive evaluation on the data of day 10 before, day 1/5/40 after the launch of Level I public health event response in Deyang Central Blood Station in 2020 and calculate the warning level. 【Results】 The warning levels of day 10 before, and day 1/5/40 after the response were blue, orange, red and blue, respectively, which were consistent with the actual situation of Deyang performing Level I public health event response at that time. 【Conclusion】 It is feasible to use fuzzy comprehensive evaluation method to build the blood inventory warning classification model in public health emergency, which provides theoretical reference for practical application.
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【Objective】 To analyze the viability of covering blood cost in medical insurance in China and discuss the necessity and practicability, so as to provide references for the improvement of medical insurance mechanism. 【Methods】 A questionnaire was designed and issued to blood centers covering 31 provinces /municipalities/autonomous regions in June 2019, and respective information regarding basic medical diagnosis and treatment directory, as well as normative documents on the official websites was collected and analyzed. 【Results】 13 out of 31 provinces /municipalities/autonomous regions had introduced the relevant policies of covering blood cost in medical insurance. Concerning the other 18 respondents, a total of 52 cities in 9 provinces had issued relevant policies. 5.01 billion RMB was included in medical insurance in 2017, accounting for 61.00% of the total clinical blood cost. 【Conclusion】 Less economic burden and less impact on voluntary blood donation recruitment could be realized by setting clinical blood price by the government.
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BACKGROUND:Animal models of atherosclerosis play an important role in the research of the pathogenesis, occurrence and development of atherosclerosis, as wel as in the prevention and treatment of atherosclerosis. OBJECTIVE:To summarize and discuss the establishment of atherosclerosis models, explore the current situation and advance of atherosclerosis models, compare the advantages and disadvantages of various methods, and provide evidence for clinical investigation. METHODS:A computer-based online search was conducted in SinoMed, VIP, Wanfang and PubMed databases by using the key words of “animal model, atherosclerosis, progression” from January 1990 to December 2014. The language was limited to both Chinese and English. Relevant articles were screened according to inclusion and exclusion criteria. The documents about the methods of atherosclerosis model preparation, method improvement as wel as their advantage and disadvantage were summarized. RESULTS AND CONCLUSION: A total of 137 articles were included. Among them, 93 articles published earlier, duplicated, and similarly were excluded, and 44 references were finaly included. The results demonstrated that, the main characteristics of models established with the high-fit diet are lipid storage. This method is commonly used due to its fixable operation. However, this method needs a long time and the position of athermanous plaque is unstable. That’s the reason why immune method, nerve and mechanical damaged method, hemodynamic method and genetic engineering method emerge. These novel methods facilitate the model establishment, and have their advantages and disadvantages. To a certain extent, they are different from human spontaneous type. Partial ligation plays irreplaceable functions when studying complications of atherosclerosis. The athermanous plaque formed by baloon injury shows accurate position, which is convenient for researchers to observe the changes of athermanous plaque after conducting al kinds of interventions. This model based on immunological method could provide guidance of vaccine research for atherosclerosis prevention. Therefore, they can choose more appropriate model formation method according to their own needs.
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The study of protein-surface interactions represents one of the most important topics in the field of biomaterials.It is believed that blood cells do not actually contact the biomaterial surface directly,but rather interact with the molecular structure of the adsorbed protein layer.Therefore,protein plays a key role in regulation and induction of cells.It provides ideas for biomaterials designing that exploring the molecular mechanism of controlling protein adsorption and regulating cell response.This paper reviews the research progress of the interactions of protein and surfaces,and prospects the future research direction.
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Objective To evaluate the long-term effect of surgical procedures for congenital choledochal cyst (CCC).Methods From 1986 to 2000, 120 cases of CCC were admitted and 73 of them underwent the primary operations in General Hospital of PLA. Three types procedures were performed,type I: external drainage of CCC in 7 cases; type II:cystojejunal Roux-en-Y anastomosis in 5 cases; type III: cyst excision with cystojejunal Roux-en-Y anastomosis or cystoduodenostomy in 57cases,and other procedures in 4 cases.Results 68 cases were followed-up for 6 months to 5 years (median 2.7 years). Three cases undergoing type I operations accepted reoperations;two cases undergoing type II operations accepted reoperations due to severe complications as cholongitis and hepatolithiasis; 57 cases treated by type III operation with the good results 88.7% and none reoperation.Conclusions External drainage is only a first-aid management on emergency basis. Internal drainage should never be done,because the effect is temporary,and severe complications result in reoperations. Cyst excision with biliary tract reconstruction is recommended as the optimal treatment of CCC.